12S ribosomal RNA

mitochondrially encoded 12S RNA
Identifiers
Symbol	MT-RNR1
Alt. symbols	MTRNR1
Entrez	4549
HUGO	7470
Other data
Locus	Chr. MT [1]

Mitochondrially encoded 12S ribosomal RNA (often abbreviated as 12S or 12S rRNA) is a component of the small subunit (SSU) of the ribosome. In humans, 12S is encoded by the MT-RNR1 gene and is 959 nt long. MT-RNR1 is one of the 37 genes contained in animal mitochondria genomes. Their 2 rRNA, 22 tRNA and 13 mRNA genes are very useful in phylogenetic studies, in particular the 12S and 16S rRNAs.

The 12S rRNA is the mitochondrial homologue of the prokaryotic 16S and eukaryotic nuclear 18S ribosomal RNAs.

Mutations in the MT-RNR1 gene may be associated with hearing loss.

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