"12:51" is a song by the American indie rock band The Strokes, written by Julian Casablancas. The song was released as the first single from their second album Room on Fire, and was released in the U.S. on November 4, 2003. It was originally known as "Supernova" before being retitled for its official release. The song is marked by the distinctive tone of Nick Valensi's lead guitar, which is reminiscent of a synthesized keyboard.

The single "12:51" charted at #7 on the UK Singles Chart and peaked at #22 on the Irish Singles Chart. In the U.S., the song charted at #15 on the Modern Rock Tracks chart.

The music video for "12:51" was directed by Roman Coppola. It resembles the computer graphic style of the 1982 film Tron.

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