Β-aminoisobutyrate

3-Aminoisobutyric acid

Names
IUPAC name 3-Amino-2-methylpropanoic acid
Other names 3-Aminoisobutyrate
Identifiers
CAS Number	144-90-1 N
3D model (JSmol)	Interactive image Interactive image
ChEBI	CHEBI:27389 Y
ChemSpider	58481 Y
ECHA InfoCard	100.005.132
KEGG	C05145 Y
PubChem CID	64956
InChI InChI=1S/C4H9NO2/c1-3(2-5)4(6)7/h3H,2,5H2,1H3,(H,6,7) Y Key: QCHPKSFMDHPSNR-UHFFFAOYSA-N Y InChI=1/C4H9NO2/c1-3(2-5)4(6)7/h3H,2,5H2,1H3,(H,6,7) Key: QCHPKSFMDHPSNR-UHFFFAOYAN
SMILES CC(CN)C(=O)O O=C(O)C(C)CN
Properties
Chemical formula	C4H9NO2
Molar mass	103.12 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N  (what is YN ?)
Infobox references

3-Aminoisobutyric acid (or β-aminoisobutyric acid, BAIBA) is a product formed by the catabolism of thymine.

During exercise, the increase of PGC-1α protein triggers the secretion of BAIBA from exercising muscles to blood (concentration 2 to 3 µM in human serum). When BAIBA reaches the white fat tissue, it activates the expression of thermogenic genes via PPARα receptors, resulting in a browning of white fat cells. One of the consequences of the BAIBA activity is the increase of the background metabolism of the BAIBA target cells.

It has recently been postulated to play a role in cell metabolism, how body burns fat and regulates insulin, triglycerides, and total cholesterol.