Ōtomo no Yakamochi (大伴 家持?, c. 718 – October 5, 785) was a Japanese statesman and waka poet in the Nara period. He is a member of the Thirty-six Poetry Immortals (三十六歌仙 sanjūrokkasen?). He was born into the prestigious Ōtomo clan; his grandfather was Ōtomo no Yasumaro and his father was Ōtomo no Tabito. Ōtomo no Sakanoe no Iratsume was his aunt. His granduncle is possibly Ōtomo no Komaro who came to Japan in the time of Empress Jitō.
The Ōtomo clan were warriors and bureaucrats in the Yamato Court, and Yakamochi served as a provincial governor (国司 kokushi?) in several provinces. Like his grandfather and father before him, Yakamochi was a well-known politician, and by Enryaku rose to the position of chūnagon (中納言?), the highest bureaucratic position.