Haemodialysis-associated amyloidosis | |
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Classification and external resources | |
Specialty | endocrinology |
ICD-10 | E85.3 |
ICD-9-CM | 277.3 |
eMedicine | med/3384 |
Haemodialysis-associated amyloidosis is a form of systemic amyloidosis associated with chronic kidney failure.
Long-term haemodialysis results in a gradual accumulation of β2 microglobulin, a serum protein, in the blood. It accumulates because it is unable to cross the dialysis filter.
Affected individuals usually present after 5 years of dialysis rarely before that. The tendency of haemodialysis-associated amyloidosis is to be articular in general affecting the joints.
Low copper dialysis is theorized to prevent or delay onset.