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Haemodialysis-associated amyloidosis

Haemodialysis-associated amyloidosis
Classification and external resources
Specialty endocrinology
ICD-10 E85.3
ICD-9-CM 277.3
eMedicine med/3384
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Haemodialysis-associated amyloidosis is a form of systemic amyloidosis associated with chronic kidney failure.

Long-term haemodialysis results in a gradual accumulation of β2 microglobulin, a serum protein, in the blood. It accumulates because it is unable to cross the dialysis filter.

Affected individuals usually present after 5 years of dialysis rarely before that. The tendency of haemodialysis-associated amyloidosis is to be articular in general affecting the joints.

Low copper dialysis is theorized to prevent or delay onset.



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