Exomedicine

Exomedicine is the study and exploration of medical solutions in the zero gravity environment of space to promote benefits to human health on Earth. The purpose is to advance the field, study, and practice of medicine on Earth through research investigations conducted in the microgravity conditions of space which may provide advances in understanding that cannot be achieved on Earth. Although the Soviet Union launched the first space station, Salyut 1 in 1971, the United States designed and launched Skylab with the intent of advancing the field of science both in space and with regards to terrestrial applications. Beginning as a “memorandum of understanding” between NASA and ESA in 1973, the first major microgravity experiments in space were carried out by “Spacelab”.Gravity is a fundamental force on earth that influences all biological systems at a molecular level. When biomedical research is conducted in Space, in so-called microgravity environments, certain earthbound limitations disappear, new and different findings are made, and living organisms behave very differently.

The term Exomedicine was coined by Kris Kimel president of the Kentucky Science and Technology Corporation and president founder of Kentucky Space LLC and a founder of Space Tango.

According to the National Institutes of Health (NIH), true microgravity cannot be truly simulated on Earth. Similarly, NIH contends that the International Space Station (ISS) has the potential to further the study of: basic biological or behavioral mechanisms associated with maintaining health or developing disease, normal or pathological physiology and metabolism, and cell repair processes and tissue regeneration that occur naturally or are enhanced through medical interventions following injury or aging. Already, several research successes have been achieved in the National Laboratory on the ISS. Findings and inferences thus far indicate that there is a rich potential to explore new and potentially game-changing insights and applications in a range of areas, that includes but is not limited to protein crystallization, 3-D tissue cultures, tissue regeneration, DNA regulation, drug and vaccine development, stem cells, and treatments for diseases such as cancer and other life-threatening and debilitating conditions. Experience with crystal growth in microgravity shows potential to yield much better results. In roughly 40 space investigations, close to 50% of the cases showed better protein crystals than any produced on Earth. Protein crystallization has three major revenue-generating applications: structural biology and drug design, bioseparations, and controlled drug delivery.

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