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UBQLN2

UBQLN2
Protein UBQLN2 PDB 1j8c.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases UBQLN2, ALS15, CHAP1, DSK2, N4BP4, PLIC2, HRIHFB2157, ubiquilin 2
External IDs MGI: 1860283 HomoloGene: 81830 GeneCards: UBQLN2
RNA expression pattern
PBB GE UBQLN2 215884 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_013444

NM_018798

RefSeq (protein)

NP_038472

NP_061268.2
NP_061268

Location (UCSC) Chr X: 56.56 – 56.57 Mb Chr X: 153.5 – 153.5 Mb
PubMed search

1J8C

NM_013444

NM_018798

NP_038472

NP_061268.2
NP_061268

Ubiquilin-2 is a protein that in humans is encoded by the UBQLN2 gene.

This gene encodes a ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and are thus thought to functionally link the ubiquitination machinery to the proteasome to effect in vivo protein degradation. This ubiquilin has also been shown to bind the ATPase domain of the Hsp70-like Stch protein.


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