LECT2

LECT2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 5B0H
Identifiers
Aliases	LECT2, chm-II, chm2, leukocyte cell derived chemotaxin 2
External IDs	MGI: 1278342 HomoloGene: 1730 GeneCards: LECT2
Gene ontology Molecular function • identical protein binding • protein binding • metal ion binding Cellular component • cytoplasm • extracellular region • extracellular space Biological process • chemotaxis • skeletal system development Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	3950	16841
Ensembl	ENSG00000145826	ENSMUSG00000021539
UniProt	O14960	O88803
RefSeq (mRNA)	NM_002302	NM_010702
RefSeq (protein)	NP_002293	NP_034832.2 NP_034832
Location (UCSC)	Chr 5: 135.92 – 135.96 Mb	Chr 13: 56.54 – 56.55 Mb
PubMed search

5B0H

3950

16841

ENSG00000145826

ENSMUSG00000021539

O14960

O88803

NM_002302

NM_010702

NP_002293

NP_034832.2
NP_034832

Leukocyte cell-derived chemotaxin-2 is a protein that in humans is encoded by the LECT2 gene, and causes Lect2 amyloidosis.

This gene encodes a secreted, 16 kDa protein that acts as a chemotactic factor to neutrophils and stimulates the growth of chondrocytes and osteoblasts. This protein has high sequence similarity to the chondromodulin repeat regions of the chicken myb-induced myeloid 1 protein. A polymorphism in this gene may be associated with rheumatoid arthritis.

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Wikipedia