The 2015 season was São Paulo's 86th year since the club's existence. At the first half of the year, São Paulo played the Campeonato Paulista and Copa Libertadores. In the state league the club's performance led to semifinals when The Dearest lose to rival Santos in a single match on away field (1-2). By the continental tournament, Tricolor reach the round of 16 being beaten by Cruzeiro in penalty shootouts by 3-4 after two equal scores (1-0 home; 0-1 away). In April, Muricy Ramalho left the São Paulo FC due to health problems and the team was trained by assistant coach Milton Cruz during a few matches and managed by Colombian Juan Carlos Osorio and Brazilian Doriva in the course of the season. After only 7 matches Doriva was replaced by Milton Cruz who trained the club again at the end of the year. In the Copa do Brasil, Tricolor was defeated by Santos in semifinals with two losses by 1-3, 2-6 on aggregate score. By national league a final 4th position take a place in the first stage of the Copa Libertadores. The main event of the year was the retirement of goalkeeper Rogério Ceni in a symbolical match between the world champions players by São Paulo in 1992 and 2005. The final result was 5-3 to 2005 champions. Rogério Ceni stopped his career at 42 with a record of 1237 matches, 131 goals during his 23 seasons by Tricolor.

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