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TUBA4A

TUBA4A
Protein TUBA4A PDB 1ffx.png
Identifiers
Aliases TUBA4A, H2-ALPHA, TUBA1, ALS22, tubulin alpha 4a
External IDs MGI: 1095410 HomoloGene: 68496 GeneCards: TUBA4A
RNA expression pattern
PBB GE TUBA4A 212242 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001278552
NM_006000

NM_009447
NM_001313723
NM_001313724

RefSeq (protein)

NP_001265481
NP_005991

NP_033473.1
NP_001300652
NP_001300653
NP_033473

Location (UCSC) Chr 2: 219.25 – 219.28 Mb Chr 1: 75.21 – 75.22 Mb
PubMed search

NM_001278552
NM_006000

NM_009447
NM_001313723
NM_001313724

NP_001265481
NP_005991

NP_033473.1
NP_001300652
NP_001300653
NP_033473

Tubulin alpha-4A chain is a protein that in humans is encoded by the TUBA4A gene.

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene encodes an alpha tubulin that is a highly conserved homolog of a rat testis-specific alpha tubulin.


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Wikipedia

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