SLCO2A1

SLCO2A1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3MRR
Identifiers
Aliases	SLCO2A1, MATR1, OATP2A1, PGT, PHOAR2, SLC21A2, solute carrier organic anion transporter family member 2A1
External IDs	MGI: 1346021 HomoloGene: 38077 GeneCards: SLCO2A1
Targeted by Drug
dinoprostone
Gene ontology Molecular function • transporter activity • lipid transporter activity • prostaglandin transmembrane transporter activity Cellular component • integral component of membrane • plasma membrane • integral component of plasma membrane • membrane Biological process • lipid transport • prostaglandin transport • transport • sodium-independent organic anion transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	6578	24059
Ensembl	ENSG00000174640	ENSMUSG00000032548
UniProt	Q92959	Q9EPT5
RefSeq (mRNA)	NM_005630	NM_033314
RefSeq (protein)	NP_005621	NP_201571.2 NP_201571
Location (UCSC)	Chr 3: 133.93 – 134.05 Mb	Chr 9: 102.99 – 103.1 Mb
PubMed search

3MRR

6578

24059

ENSG00000174640

ENSMUSG00000032548

Q92959

Q9EPT5

NM_005630

NM_033314

NP_005621

NP_201571.2
NP_201571

Solute carrier organic anion transporter family, member 2A1 also known as the prostaglandin transporter (PGT) is a protein that in humans is encoded by the SLCO2A1 gene.

This gene encodes a prostaglandin transporter that is a member of the 12-membrane-spanning organic anion-transporting polypeptide superfamily of transporters. The encoded protein may be involved in mediating the uptake and clearance of prostaglandins in numerous tissues.

Mutations in this gene have been shown to cause primary hypertrophic osteoarthropathy.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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