Pyridoxine

Pyridoxine

Pyridoxine
Clinical data
AHFS/Drugs.com	Monograph
Pregnancy category	US: A, C
Routes of administration	by mouth, IV, IM, subQ
ATC code	A11HA02 (WHO)
Identifiers
IUPAC name 4,5-Bis(hydroxymethyl)-2-methylpyridin-3-ol
Synonyms	vitamin B6, pyridoxol
CAS Number	65-23-6
DrugBank	DB00165
ChemSpider	1025
UNII	KV2JZ1BI6Z
KEGG	D08454
ChEBI	CHEBI:16709
ChEMBL	CHEMBL1364
ECHA InfoCard	100.000.548
Chemical and physical data
Formula	C8H11NO3
Molar mass	169.18 g·mol−1
3D model (Jmol)	Interactive image
Melting point	159 to 162 °C (318 to 324 °F)
SMILES CC1=NC=C(C(=C1O)CO)CO
InChI InChI=1S/C8H11NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,10-12H,3-4H2,1H3  Y Key:LXNHXLLTXMVWPM-UHFFFAOYSA-N

Pyridoxine, also known as vitamin B₆ and pyridoxol, is a form of vitamin B₆ found commonly in food and used as dietary supplement. As a supplement it is used to treat and prevent pyridoxine deficiency, sideroblastic anaemia, pyridoxine-dependent epilepsy, certain metabolic disorders, problems from isoniazid, and mushroom poisoning. It is used by mouth or by injection.

It is usually well tolerated. Occasionally side effects include headache, numbness, and sleepiness. Normal doses are safe during pregnancy and breastfeeding. Pyridoxine is in the vitamin B family of vitamins. It is required by the body to make amino acids, carbohydrates, and lipids. Sources in the diet include fruit, vegetables, and grain.

Pyridoxine was discovered in 1934, isolated in 1938, and first made in 1939. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Pyridoxine is available as a generic medication and over the counter. The wholesale cost in the developing world is about 0.59 to 3.54 USD per month. Foods, such as breakfast cereal have pyridoxine added in some countries.