Names | |
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IUPAC name
2-Phenoxyethanol
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Other names
Phenoxyethanol
Ethylene glycol monophenyl ether Phenoxytolarosol Dowanol EP / EPH Protectol PE Emery 6705 Rose ether 1-Hydroxy-2-phenoxyethane β-hydroxyethyl phenyl ether Phenyl cellosolve |
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Identifiers | |
122-99-6 | |
3D model (Jmol) | Interactive image |
ChEBI | CHEBI:64275 |
ChEMBL | ChEMBL1229846 |
ChemSpider | 13848467 |
ECHA InfoCard | 100.004.173 |
PubChem | 31236 |
UNII | HIE492ZZ3T |
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Properties | |
C8H10O2 | |
Molar mass | 138.17 g·mol−1 |
Appearance | Colorless oily liquid |
Odor | faint rose-like |
Density | 1.102 g/cm3 |
Melting point | −2 °C (28 °F; 271 K) |
Boiling point | 247 °C (477 °F; 520 K) |
26 g/kg | |
Solubility | Chloroform, Alkali, diethyl ether: soluble |
Solubility in arachis oil | slightly |
Solubility in olive oil | slightly |
Solubility in acetone | miscible |
Solubility in ethanol | miscible |
Solubility in glycerol | miscible |
Vapor pressure | 0.001 kPa |
Thermal conductivity | 0.169 W/(m⋅K) |
Refractive index (nD)
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1.534 (20 ℃) |
Hazards | |
NFPA 704 | |
Flash point | 121 °C (250 °F; 394 K) |
Related compounds | |
Related compounds
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phenetole |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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what is ?) | (|
Infobox references | |
Phenoxyethanol is a germicidal and germistatic glycol ether, phenol ether, and aromatic alcohol often used together with quaternary ammonium compounds.
Phenoxyethanol is used as a perfume fixative; an insect repellent; an antiseptic; a solvent for cellulose acetate, dyes, inks, and resins; a preservative for pharmaceuticals, cosmetics and lubricants; an anesthetic in fish aquaculture; and in organic synthesis.
Phenoxyethanol is an alternative to formaldehyde-releasing preservatives. In Japan and the EU, its concentration in cosmetics is restricted to 1%.
Phenoxyethanol is produced by the hydroxyethylation of phenol (Williamson synthesis), for example, in the presence of alkali-metal hydroxides or alkali-metal borohydrides.
Phenoxyethanol is effective against gram-negative and gram-positive bacteria, and the yeast Candida albicans.
Phenoxyethanol is a vaccine preservative and potential allergen, which may result in a nodular reaction at the site of injection. It reversibly inhibits NMDAR-mediated ion currents. Ingestion may cause CNS and respiratory depression, vomiting and diarrhea in infants, particularly when combined with chlorphenesin.