OGN (gene)

OGN
Identifiers
Aliases	OGN, OG, OIF, SLRR3A, osteoglycin
External IDs	MGI: 109278 HomoloGene: 8542 GeneCards: OGN
Gene ontology Molecular function • protein binding • growth factor activity Cellular component • extracellular vesicle • extracellular matrix • proteinaceous extracellular matrix • extracellular region • lysosomal lumen • Golgi lumen • extracellular exosome • extracellular space Biological process • negative regulation of smooth muscle cell proliferation • axonogenesis • keratan sulfate catabolic process • keratan sulfate biosynthetic process Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	4969	18295
Ensembl	ENSG00000106809	ENSMUSG00000021390
UniProt	P20774	Q62000
RefSeq (mRNA)	NM_033014 NM_014057 NM_024416	NM_008760
RefSeq (protein)	NP_054776 NP_077727 NP_148935 NP_054776.1 NP_148935.1	NP_032786
Location (UCSC)	Chr 9: 92.38 – 92.4 Mb	Chr 13: 49.61 – 49.62 Mb
PubMed search

4969

18295

ENSG00000106809

ENSMUSG00000021390

P20774

Q62000

NM_033014
NM_014057
NM_024416

NM_008760

NP_054776
NP_077727
NP_148935
NP_054776.1
NP_148935.1

NP_032786

Osteoglycin (also called mimecan), encoded by the OGN gene, is a human protein.

This gene encodes a protein which induces ectopic bone formation in conjunction with transforming growth factor beta. This protein is a small proteoglycan which contains tandem leucine-rich repeats (LRR). The gene expresses three transcript variants.

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Wikipedia