Norman Pirie
| Norman Pirie | |
|---|---|
| Born | 1 July 1907 Easebourne, West Sussex |
| Died |
29 March 1997 (aged 89) Harpenden, Hertfordshire |
| Fields | virology |
| Institutions | Rothamsted Experimental Station |
| Alma mater | Cambridge University |
| Known for | crystallization of [tomato bushy stunt virus] |
| Notable awards | Copley Medal in 1971 |
Norman Wingate (Bill) Pirie FRS (1 July 1907 – 29 March 1997), was a British biochemist and virologist who, along with Frederick Bawden, discovered that a virus can be crystallized by isolating tomato bushy stunt virus in 1936. This was an important milestone in understanding DNA and RNA.
Pirie was born in Easebourne, near Midhurst in West Sussex, the youngest of three children of Sir George Pirie, a Scottish painter, and his wife while they were on a visit to England. He was raised near Torrance, East Dunbartonshire. He developed a stammer, and was educated by private tutors and then spent periods at Kelvinside Academy in Glasgow, Harriston School near Dumfries, and Hastings Grammar School, and then from 1921 to 1925 at Rydal School in Colwyn Bay. He studied natural sciences (biochemistry) at Emmanuel College, Cambridge from 1925 to 1929, and became a demonstrator after graduating. He married fellow biochemist Antoinette (Tony) Patey in 1931. They had a son and a daughter.
He worked at Cambridge University until 1940, working with Sir Frederick Gowland Hopkins. From 1932, he worked with Ashley Miles on the Brucella bacteria responsible for brucellosis, and with Frederick Bawden on potato viruses. They studied the tobacco mosaic virus, demonstrating that the virus contained ribonucleic acid (when others claimed they were just proteins). Bawden moved to Rothamsted Experimental Station in Harpenden in 1936, and Pirie also moved to Rothamsted as a virus physiologist in 1940, becoming head of the biochemistry department in 1947. During the Second World War, Pirie investigated the possibility of extracting edible proteins from leaves. Experiments on extracting edible leaf proteins continued into the 1970s.
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