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Muscle ache

Myalgia
Classification and external resources
Specialty Rheumatology
ICD-10 M79.1
ICD-9-CM 729.1
DiseasesDB 22895
MedlinePlus 003178
MeSH D063806
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Myalgia, or muscle pain, is a symptom of many diseases and disorders. The most common causes are the overuse or over-stretching of a muscle or group of muscles. Myalgia without a traumatic history is often due to viral infections. Longer-term myalgias may be indicative of a metabolic myopathy, some nutritional deficiencies or chronic fatigue syndrome.

The most common causes of myalgia are overuse, injury or strain. However, myalgia can also be caused by diseases, disorders, medications, or as a response to a vaccination. It is also a sign of acute rejection after heart transplant surgery.

The most common causes are:

Muscle pain occurs with:

Overuse of a muscle is using it too much, too soon and/or too often. Examples are:

The most common causes of myalgia by injury are: sprains and strains.

Multiple sclerosis (neurologic pain interpreted as muscular), Myalgic Encephalomyelitis, Myositis, Mixed connective tissue disease, Lupus erythematosus, Familial Mediterranean fever, Polyarteritis nodosa, Devic's disease, Morphea, Sarcoidosis

Carnitine palmitoyltransferase II deficiency, Conn's syndrome, Adrenal insufficiency, Hyperthyroidism, Hypothyroidism, postorgasmic illness syndrome (POIS).


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