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List of fictional diseases


This article is a list of fictional diseases, disorders, infections, and pathogens which appear in fiction where they have a major plot or thematic importance. They may be fictional psychological disorders, magical, from mythological or fantasy settings, have evolved naturally, been genetically modified (most often created as biological weapons), or be any illness that came forth from the (ab)use of technology.

Items in this list are followed by a brief description of symptoms and other details.

Cassandra Clare

Mundanes are immune to the disease, as demon pox is assumed to be caused by the interaction of demon poisons with the angelic nature of Shadowhunters.

Transmetropolitan

by John J. Lardieri

Similar to the Black Death and HIV/AIDS among Humans, the Drafa Plague bears a stigma among the Markab as a disease that the public felt was only caught by those considered sinful, immoral or unclean by Markab standards, and a punishment by their gods for committing such acts. The disease was named after an island on their homeworld where its inhabitants were wiped out by the disease, an island noted in Markab history for its decadence and immorality. The story of the island was eventually used to frighten small Markab children into behaving. Even accusing a Markab of being infected with the disease can bring shame, paranoia, fear, and an angry response from the accused, and Markab doctors would frequently certify someone's death from the disease as death by natural causes, so the family could avoid a scandal and the implied accusation that they or their family were unclean or immoral.

Although fictional, a viral "Walk Across America For Groats Disease" begins every March 21 from Springboro, Ohio. The "Walk" takes about six months to reach the final destination in California and raises millions of dollars (fictitious) for Groats Disease victims.


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