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Impaired glucose tolerance

Impaired glucose tolerance
Classification and external resources
ICD-10 R73.0
ICD-9-CM 790.21
MeSH D018149
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Impaired glucose tolerance (IGT) is a pre-diabetic state of hyperglycemia that is associated with insulin resistance and increased risk of cardiovascular pathology. IGT may precede type 2 diabetes mellitus by many years. IGT is also a risk factor for mortality.

According to the criteria of the World Health Organization and the American Diabetes Association, impaired glucose tolerance is defined as:

From 10 to 15 percent of adults in the United States have impaired glucose tolerance or impaired fasting glucose.

The risk of progression to diabetes and development of cardiovascular disease is greater than for impaired fasting glucose.

Although some drugs can delay the onset of diabetes, lifestyle modifications play a greater role in the prevention of diabetes. Patients identified as having an IGT may be able to prevent diabetes through a combination of increased exercise and reduction of body weight. "Drug therapy can be considered when aggressive lifestyle interventions are unsuccessful."


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