Gripe water

Gripe water is a product sold to relieve colic and other gastrointestinal ailments and discomforts of infants. Little evidence supports the efficacy of gripe water. Its use usually does not pose risk to the infant, unless the formulation includes alcohol or sugar.

The first gripe water was formulated in England in 1851. Gripe water was invented by William Woodward, an English pharmacist who did his apprenticeship in Boston, Lincolnshire, and later bought a business in Nottingham. Gripe water was adopted as a prescription by physicians. In the 1840s babies in Eastern England were afflicted by a condition known as "fen fever", and during that time there was also an outbreak of malaria in England. Woodward took his inspiration from the treatments for malaria and "fen fever". He noted that the formula used to treat fen fever was an effective "soother of fretful babies and provided relief from gastrointestinal troubles in infants." The original Woodward's Gripe Water contained 3.6% alcohol, dill oil, sodium bicarbonate, sugar, and water. Woodward registered "Gripe Water" as a trademark in 1876. It was initially marketed with the slogan "Granny told Mother and Mother told me."

In 1993, the United States Food and Drug Administration ordered an automatic detention of all shipments of Woodward's into the U.S. on the basis of its being an unapproved drug. In response to the FDA's import alert, Woodward's and other manufacturers have continued marketing the products, but as a dietary supplement.

The formulation now varies according to the country of manufacture. In many countries, including the original source country (UK), alcohol and sucrose have been replaced with other ingredients. However, sodium bicarbonate, dill oil and fennel oil continue to be the main active ingredients. While evidence of gripe water's effectiveness has been limited to anecdotal accounts, there has been speculation about the reasons for the perceived effectiveness of gripe water. Its commercial success has led to imitations, including some that have strayed substantially from the original formulation.

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