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Glutaraldehyde

Glutaraldehyde
Skeletal formula of glutaraldehyde
Ball-and-stick model of the glutaraldehyde molecule
Names
Preferred IUPAC name
Pentanedial
Other names
Glutaraldehyde
Glutardialdehyde
Glutaric acid dialdehyde
Glutaric aldehyde
Glutaric dialdehyde
1,5-Pentanedial
Identifiers
111-30-8 YesY
3D model (Jmol) Interactive image
ChemSpider 3365 YesY
DrugBank DB03266 YesY
ECHA InfoCard 100.003.506
KEGG D01120 YesY
PubChem 3485
UNII T3C89M417N YesY
Properties
C5H8O2
Molar mass 100.117
Appearance Clear liquid
Odor pungent
Density 1.06 g/mL
Melting point −14 °C (7 °F; 259 K)
Boiling point 187 °C (369 °F; 460 K)
Miscible, reacts
Vapor pressure 17 mmHg (20°C)
Hazards
Flash point noncombustible
US health exposure limits (NIOSH):
PEL (Permissible)
none
REL (Recommended)
C 0.2 ppm (0.8 mg/m3)
IDLH (Immediate danger)
N.D.
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
YesY  (what is YesYN ?)
Infobox references

Glutaraldehyde, sold under the brandname Glutaral among others, is a disinfectant and medication. As a disinfectant it is used to sterilize surgical instruments and other other areas. As a medication it is used to treat warts on the bottom of the feet. It is applied as a liquid.

Side effects include skin irritation. If exposed to large amounts nausea, headache, and shortness of breath may occur.Protective equipment is recommended when used. Glutaraldehyde is effective against a range of microorganisms including spores. It works by a number of mechanisms.

Glutaraldehyde came into medical use in the 1960s. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about 1.50 to 7.40 USD per liter of 2% solution. It is sold under a number of brand names including Cidex. There are a number of other commercial uses such as leather tanning.

Virtually all applications of glutaraldehyde exploit its high reactivity toward proteins. Being nonvolatile and bifunctional, glutaraldehyde is often preferred to the less expensive formaldehyde. It reacts with amines, amides, and thiol groups in proteins.

A glutaraldehyde solution of 0.1% to 1.0% concentration may be used as a biocide for system disinfection and as a preservative for long term storage. It is a sterilant, killing endospores in addition to many microorganisms and viruses.

Glutaraldehyde is a component of hydraulic fracturing "fracking" fluid. It is included in the additive called Alpha 1427, as a biocide. Bacterial growth can impair the production of oil and gas wells, and can be introduced into the formation from various sources including the source water, proppant, and polymers used in the hydraulic fracturing process. Glutaraldehyde is pumped as a liquid additive with the fracturing fluid to reduce or eliminate this source of formation and fracture conductivity damage.


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Wikipedia

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