Essentiale
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| Trade names | Essentiale |
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Essentiale (polyenylphosphatidylcholine or PPC, with or without synergistic vitamins) is a preparation of essential phospholipids. Essentiale normalizes the metabolism of lipids and proteins, improves the detoxification function of the liver, restores the cellular structure of the liver and retards the producing of conjunctive tissue. Essentiale medications are indicated for the treatment of fatty degeneration of the liver, hepatitis (including toxic hepatitis, liver damage caused by medicines or alcohol abuse), cirrhosis of the liver, and disturbances in liver function associated with different illnesses.
Phospholipids are essential structural components of all cellular membranes. Essential phospholipids (EPL substance -- an active ingredient in Essentiale medications) is a complex of substances of natural origin (ethers of cholinephosphoric acid (phosphatidylcholine) and unsaturated fatty acids (linoleic, linolenic, olein). Essentiale medications possess membranotropic properties, exert metabolic and hepatoprotective action, and regulate lipid and carbohydrate metabolism. Essential phospholipids increase the functional status of the liver.
Intervening in the disturbance of the liver's metabolism, Essential phospholipids enter the cell membrane and combine with the endogenous phospholipids. Essential phospholipids improve the patient's clinical status and the liver's lab indices.
Combination of Essentiale with cordiamin (nikethamide) and vitamin E (50 mg/kg for 35 days) considerably activates the mono-oxygenase, glucoro- and glutathione transferase systems of the liver, resulting in the free-radical processes becoming less intense.
The spectrum of Essential phospholipids' activity in chronic degenerative liver diseases is illustrated by the following properties:
Essentiale is used to treat the following diseases:
Essentiale medications are manufactured under 4 trade names:
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