Cystatin C

CST3

Crystal structure of human cystatin C monomer.png

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1G96, 1R4C, 1TIJ, 3GAX, 3NX0, 3PS8, 3QRD, 3S67, 3SVA

Identifiers

CST3, ARMD11, HEL-S-2, cystatin C

External IDs

OMIM: 604312 MGI: 102519 HomoloGene: 78 GeneCards: CST3

Gene ontology
Molecular function	• peptidase inhibitor activity • cysteine-type endopeptidase inhibitor activity • beta-amyloid binding • protein binding • identical protein binding • endopeptidase inhibitor activity • protease binding
Cellular component	• extracellular region • extracellular exosome • extracellular space • tertiary granule lumen • ficolin-1-rich granule lumen
Biological process	• negative regulation of proteolysis • cellular protein metabolic process • defense response • negative regulation of peptidase activity • negative regulation of extracellular matrix disassembly • regulation of tissue remodeling • negative regulation of blood vessel remodeling • negative regulation of elastin catabolic process • negative regulation of collagen catabolic process • neutrophil degranulation • supramolecular fiber organization • negative regulation of endopeptidase activity
Sources:Amigo / QuickGO

RNA expression pattern

PBB GE CST3 201360 at tn.png

More reference expression data

Orthologs

Species

Human

Mouse


1471


13010


ENSG00000101439


ENSMUSG00000027447


P01034


P21460

RefSeq (mRNA)


NM_001288614 NM_000099


NM_009976

RefSeq (protein)


NP_000090 NP_001275543


NP_034106.2 NP_034106

Location (UCSC)

Chr 20: 23.63 – 23.64 Mb

Chr 2: 148.87 – 148.88 Mb

PubMed search

1G96, 1R4C, 1TIJ, 3GAX, 3NX0, 3PS8, 3QRD, 3S67, 3SVA

ENSG00000101439

ENSMUSG00000027447

NM_001288614
NM_000099

NP_000090
NP_001275543

NP_034106.2
NP_034106

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Wikipedia

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