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Cetyl myristoleate

Cetyl myristoleate
Cetyl myristoleate.svg
Names
IUPAC name
Hexadecyl (Z)-tetradec-9-enoate
Other names
cis-9-Cetyl myristoleate
Identifiers
3D model (JSmol)
ChemSpider
PubChem CID
UNII
Properties
C30H58O2
Molar mass 450.79 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N  (what is YesYN ?)
Infobox references

Cetyl myristoleate is a chemical compound which is a type of fatty acid ester or, more specifically, a cetylated fatty acid (CFA). It is the cetyl ester of myristoleic acid. Although it is used as a dietary supplement, there is little clinical evidence to support a benefit for any medical condition.

Cetyl myristoleate has been prepared by an esterification reaction between myristoleic acid and cetyl alcohol, catalyzed by p-toluenesulfonic acid monohydrate.

In animal studies, cetyl myristoleate was first reported to block inflammation and prevent adjuvant-induced arthritis at very high doses in rats. Other studies using identical and similar methods have failed to replicate this effect. In follow-up studies in mice, a modest anti-inflammatory effect was observed.

Although cetyl myristoleate is sold as a dietary supplement, its possible benefits in the treatment of any medical condition are largely unknown and the Federal Trade Commission has taken legal action against supplement manufacturers for exaggerated claims.

There is some clinical evidence for the benefits of CFAs, which may contain cetyl myristoleate, in arthritic patients. One pilot study found that cetyl myristoleate may be beneficial against fibromyalgia. However, these low-quality clinical trials provide only limited scientific evidence of efficacy.


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