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    Gene therapy

    • This piglix contains articles or sub-piglix about Gene therapy

    • Antisense therapy

    • Antisense therapy is a form of treatment for genetic disorders or infections. When the genetic sequence of a particular gene is known to be causative of a particular disease, it is possible to synthesize a strand of nucleic acid (DNA, RNA or a chemical analogue) that will bind to the messenger RNA (mRNA) produced by th ... Read »


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    • Gene therapy

    • Gene therapy is the therapeutic delivery of nucleic acid polymers into a patient's cells as a drug to treat disease. The first attempt at modifying human DNA was performed in 1980 by Martin Cline, but the first successful and approved nuclear gene transfer in humans was performed in May 1989. The first therapeutic use ... Read »


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    • Gene therapy for color blindness

    • Gene therapy for color blindness is an experimental gene therapy aiming to convert congenitally colorblind individuals to trichromats by introducing a photopigment gene that they lack. Though partial color blindness is considered only a mild disability and is controversial whether it is even a disorder, it is a conditi ... Read »


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    • Gene therapy for epilepsy

    • Gene therapy is being studied for some forms of epilepsy. It relies on viral or non-viral vectors to deliver DNA or RNA to target brain areas where seizures arise, in order to prevent the development of epilepsy or to reduce the frequency and/or severity of seizures. Gene therapy has delivered promising results in earl ... Read »


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    • Gene therapy for osteoarthritis

    • Gene transfer strategies for medical management of the Osteoarthritis have attracted the attention of scientists due to the complex pathology of this chronic disease. Unlike other pharmacological treatments, gene therapy targets the disease process rather than the symptoms. Passing from parents to children, genes ... Read »


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    • Gene therapy in Parkinson's disease


    • Gene therapy of the human retina

    • Retinal gene therapy holds great promise in treating different forms of non-inherited and inherited blindness. In 2008, three independent research groups reported that patients with the rare genetic retinal disease Leber's Congenital Amaurosis had been successfully treated using gene therapy with adeno-associated viru ... Read »


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    • Strategies for Engineered Negligible Senescence

    • Strategies for Engineered Negligible Senescence (SENS) is the term coined by British biogerontologist Aubrey de Grey for the diverse range of regenerative medical therapies, either planned or currently in development, for the periodical repair of all age-related damage to human tissue with the ultimate purpose of maint ... Read »


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    • Strimvelis

    • Strimvelis is the first ex-vivo stem cell gene therapy to treat patients with a very rare disease called ADA-SCID (Severe Combined Immunodeficiency due to Adenosine Deaminase deficiency), a rare disorder caused by the absence of an essential protein called adenosine deaminase (ADA), which is required for the production ... Read »


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    • Synthetic rescue

    • Synthetic rescue (or synthetic recovery or synthetic viability when a lethal phenotype is rescued) refers to a genetic interaction in which a cell that is nonviable or sensitive to a specific drug due to the presence of a genetic mutation becomes viable when the original mutation is combined with a second mutation in a ... Read »


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