Gene ontology
Molecular function	• protein homodimerization activity • aminoacylase activity • peroxidase activity • metal ion binding • oxidoreductase activity, acting on peroxide as acceptor • catalase activity • antioxidant activity • heme binding • NADP binding • enzyme binding • oxidoreductase activity • receptor binding
Cellular component	• cytosol • Golgi apparatus • membrane • intracellular membrane-bounded organelle • focal adhesion • mitochondrial intermembrane space • peroxisomal membrane • peroxisome • plasma membrane • peroxisomal matrix • endoplasmic reticulum • mitochondrion • lysosome • extracellular exosome • extracellular region • extracellular space • secretory granule lumen • ficolin-1-rich granule lumen
Biological process	• response to phenylpropanoid • ureteric bud development • response to estradiol • response to hypoxia • response to cadmium ion • response to fatty acid • kidney development • response to inactivity • response to reactive oxygen species • response to hyperoxia • cellular response to growth factor stimulus • aging • cholesterol metabolic process • response to L-ascorbic acid • negative regulation of apoptotic process • purine nucleotide catabolic process • response to ozone • response to oxidative stress • response to activity • protein tetramerization • response to vitamin E • response to insulin • response to vitamin A • aerobic respiration • response to lead ion • positive regulation of NF-kappaB transcription factor activity • osteoblast differentiation • hydrogen peroxide catabolic process • UV protection • positive regulation of phosphatidylinositol 3-kinase signaling • response to radiation • response to light intensity • response to ethanol • negative regulation of NF-kappaB transcription factor activity • oxidation-reduction process • triglyceride metabolic process • protein homotetramerization • response to UV • response to toxic substance • response to hydrogen peroxide • response to drug • hemoglobin metabolic process • positive regulation of cell division • cellular oxidant detoxification • neutrophil degranulation
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


847


12359

Ensembl


ENSG00000121691


ENSMUSG00000027187

UniProt


P04040


P24270

RefSeq (mRNA)


NM_001752


NM_009804

RefSeq (protein)


NP_001743


NP_033934.2 NP_033934

Location (UCSC)

Chr 11: 34.44 – 34.47 Mb

Chr 2: 103.45 – 103.49 Mb

PubMed search

1DGB, 1DGF, 1DGG, 1DGH, 1F4J, 1QQW

NP_033934.2
NP_033934

Catalase is a common enzyme found in nearly all living organisms exposed to oxygen (such as bacteria, plants, and animals). It catalyzes the decomposition of hydrogen peroxide to water and oxygen. It is a very important enzyme in protecting the cell from oxidative damage by reactive oxygen species (ROS). Likewise, catalase has one of the highest turnover numbers of all enzymes; one catalase molecule can convert millions of hydrogen peroxide molecules to water and oxygen each second.

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Wikipedia