ABCF1

ABCF1
Identifiers
Aliases	ABCF1, ABC27, ABC50, ATP binding cassette subfamily F member 1
External IDs	MGI: 1351658 HomoloGene: 849 GeneCards: ABCF1
Gene ontology Molecular function • nucleotide binding • ribosome binding • translation activator activity • translation factor activity, RNA binding • ATPase activity • protein binding • poly(A) RNA binding • ATP binding Cellular component • cytoplasm • ribosome • nuclear envelope • membrane • nucleoplasm • nucleus • polysomal ribosome • cytosol Biological process • translation • ribosome biogenesis • positive regulation of translation • transmembrane transport • translational initiation • inflammatory response Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	23	224742
Ensembl	n/a	ENSMUSG00000038762
UniProt	Q8NE71	Q6P542
RefSeq (mRNA)	NM_001090 NM_001025091	NM_013854
RefSeq (protein)	NP_001020262 NP_001081	NP_038882.1
Location (UCSC)	Chr 6: 30.57 – 30.6 Mb	Chr 17: 35.96 – 35.97 Mb
PubMed search

23

224742

n/a

ENSMUSG00000038762

Q8NE71

Q6P542

NM_001090
NM_001025091

NM_013854

NP_001020262
NP_001081

NP_038882.1

ATP-binding cassette sub-family F member 1 is a protein that in humans is encoded by the ABCF1 gene.

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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